User blog comment:TheAzumangaDaiohFan/Opinions On The Fallout Series? 11/21/15/@comment-4749112-20151122010509/@comment-24101790-20151122011041

The 2nd really builds on the series and injects a lot more humor into it with cultural references/inside jokes (it's the better game IMO). That being said, the first few games differ drastically from Fallout: 3 and onward so it really depends on how much of the lore/history you want to know.